研究業績

2019年

Recent advances in asymmetric phosphine oxide catalysis
Kotani, S.; Nakajima, M.
Tetrahedron Lett. In press.
[doi:https://doi.org/10.1016/j.tetlet.2019.151421]

Recent advances in asymmetric phosphine oxide catalysis
Kotani, S.; Nakajima, M.
Tetrahedron Lett. In press.
[doi:https://doi.org/10.1016/j.tetlet.2019.151421]

Lewis Base-catalyzed Enantioselective Conjugate Reductions of β,β-Disubstituted α,β-Unsaturated Ketones with Trichlorosilane: E/Z Isomerization, Regioselectivity, and Synthetic Applications
Sugiura, M.; Ashikari, Y.; Takahashi, Y.; Yamaguchi, K.; Kotani, S.; Nakajima, M.
J. Org. Chem. 2019, 84, 11458-11473.
[doi:https://doi.org/10.1021/acs.joc.9b01298]

Selective Monoacylation of Diols and Asymmetric Desymmetrization of Dialkyl meso-Tartrates Using 2-Pyridyl Esters as Acylating Agents and Metal Carboxylates as Catalysts
Hashimoto, Y.; Michimuko, C.; Yamaguchi, K.; Nakajima, M.; Sugiura, M.
J. Org. Chem. 2019, 84, 9313–9321.
[doi:https://doi.org/10.1021/acs.joc.9b00827]

Phosphine Oxide-Catalyzed Asymmetric Aldol Reactions and Double Aldol Reactions
Kotani, S.
Chem. Pharm. Bull. 2019, 67, 519–526.
[doi:https://doi.org/10.1248/cpb.c19-00169]

Stereoselective Synthesis of 2-Fluoro-1,3-Diols via Lithium Binaphtholate-Catalyzed Aldol–Tishchenko Reaction
Asano, T.; Kotani, S.; Nakajima, M.
Org. Lett. 2019, 21, 4192-4196.
[doi:https://doi.org/10.1021/acs.orglett.9b01371]

Lithium Binaphtholate-Catalyzed Michael Reaction of Malonates with Maleates and Its Application to the Enantioselective Synthesis of Tricarboxylic Acid Derivatives
Sakamoto, M.; Kaneko, T.; Orito, Y.; Shimoda, Y.; Nakajima, M.
Chem. Pharm. Bull. 2019, 67, 452-460.
[doi: https://doi.org/10.1248/cpb.c18-00993]

2018年

Catalytic Enantioselective Aldol Reactions of Unprotected Carboxylic Acids under Phosphine Oxide Catalysis
Kotani, S.; Yoshiwara, Y.; Ogasawara, M.; Sugiura, M.; Nakajima, M.
Angew. Chem. In. Ed. 2018, 57, 15877- 15881.
[doi: dx.doi.org/10.1002/anie.201810599]

Dramatic Enantioselectivity Reversal in the Propargylation of Aldehyde with Alkynyllithium Catalyzed by Dilithium Binaphtholate Derivatives
Nakajima, M.; Watanabe, R.; Osakama, K.; Sakamoto, M.; Takemoto, D.; Kukita, K.
Heterocycles 2018, 97, 708-711.
[doi: 10.3987/COM-18-S(T)63]

2017年

Stereoselective Synthesis of Nitrogen-Containing Compounds from Enamines
Sugiura, M.; Kashiwagi, T.; Ito, M.; Kotani, S.; Nakajima, M.
J. Org. Chem. 2017, 82, 10968-10979.
[doi: dx.doi.org/10.1021/acs.joc.7b01923]

Sequential Catalysis of Phosphine Oxide for Stereoselective Synthesis of Stereopentads
Kotani, S.; Kai, K.; Sugiura, M.; Nakajima, M.
Org. Lett. 2017, 19, 3672-3675.
[doi: dx.doi.org/10.1021/acs.orglett.7b01719]

Chiral lithium binaphtholate for enantioselective amination of acyclic α-alkyl-β-keto esters: Application to the total synthesis of L-carbidopa
Asano, T.; Moritani, M.; Nakajima, M.; Kotani, S.
Tetrahedron 2017, 73, 5975-5982.
[doi: dx.doi.org/10.1016/j.tet.2017.08.015]

The 2016 Kumamoto earthquake; reconstruction and countermeasures
Ishikawa, H.; Nishino, H.; Nakajima, M.; Kotani, S.
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 2017, 75, 259-263
[doi: dx.doi.org/10.5059/yukigoseikyokaishi.75.259]

Enantioselective chlorinative aldol reaction of α-substituted acroleins catalyzed by chiral phosphine oxides
Kotani, S.; Hanamure, T.; Nozaki, H.; Sugiura, M.; Nakajima, M.
Tetrahedron: Asymmetry, 2017, 28, 282-287.
[doi: dx.doi.org/10.1016/j.tetasy.2017.01.006]

Asymmetric aldol/vinylogous aldol/cyclization reaction using phosphine oxide catalysts
Alim, N.R.; Miyazaki, S.; Shimoda, Y.; Sugiura, M.; Nakajima, M.; Kotani, S.
Chem. Pharm. Bull. 2017, 65, 989-993.
[doi: dx.doi.org/10.1248/cpb.c17-00540]

2016年

Enantioselective Michael Addition of a Malonic Ester to a Maleic Ester Catalyzed by Lithium Binaphtholate
Sakamoto, M.: Kaneko, T.: Orito, Y.: Nakajima, M.
Synlett 2016, 27, 2477-2480.
[DOI: 10.1055/s-0035-1562691]

Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress- mediated expression of myostatin and atrogin-1
Enoki, Y., Watanabe, H., Arake, R., Sugimoto, R.; Imafuku, T.; Tominaga, Y.; Ishima, Y.; Kotani, S.; Nakajima, M.; Tanaka, M.; MAtsushita, K.; Fukagawa, M.; Otagiri, M.; Maruyama, T.
Sci. Rep. 2016, 6, 32084.
[doi: 10.1038/srep32084]

Concise Asymmetric Construction of C2 -symmetric 1,9-Diarylnonanoids Using a Hypervalent Silicon Complex: Total Synthesis of (-)-Ericanone
Kotani, S.; Kai, K.; Shimoda, Y.; Sugiura, M.; Ogasawara, M.; Nakajima, M.
Chem. Asian J. 2016, 11, 376-379.

[doi: 10.1002/asia.201501080]

Stereoselective synthesis of highly functionalized 2,3-dihydro-4-pyranones using phosphine oxide as catalyst
Kotani, S.; Miyazaki, S.; Kawahara, K.; Shimoda, Y.; Sugiura, M.; Nakajima, M.
Chem. Pharm. Bull. 2016, 64, 189-192.
[doi: dx.doi.org/10.1248/cpb.c15-00806]

Asymmetric Direct 1,2-Addition of Aryl Grignard Reagents to Aryl Alkyl Ketones
Osakama, K.; Nakajima, M.
Org. Lett. 2016, 18, 236-239.
[doi: 10.1021/acs.orglett.5b03379]

Enantioselective amination of acyclic α-alkylated β-keto esters catalyzed by chiral lithium binaphtholate
Kotani, S.; Asano, T.; Moritani, M.; Nakajima, M.
Tetrahedron Lett. 2016, 57, 4217-4219.
[doi: dx.doi.org/10.1016/j.tetlet.2016.08.013]

2010〜2015年

A Sterically Congested α-Cyanoamine as a Cyanating Reagent: Cyanation of Acetals and Orthoesters
Kotani, S.; Sakamoto, M.; Osakama, K.; Nakajima, M.
Eur. J. Org. Chem. 2015, 30, 6606-6609.
[doi: dx.doi.org/10.1002/ejoc.201501084]

Nitration of indoxyl sulfate facilitates its cytotoxicity in human renal proximal tubular cells via expression of heme oxygenase-1
Ishima, Y.; Narisoko, T.; Kragh-Hansen, U., Kotani, S.; Nakajima, M.; Otagiri, M;, Maruyama, T.
Biochemical and Biophysical Research Communications 2015, 465, 481-487
[doi: dx.doi.org/10.1016/j.bbrc.2015.08.043]

One-Pot Synthesis of β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds
Sugiura, M.; Ashikari, Y.; Nakajima, M.
J. Org. Chem. 2015, 80, 8830-8835
[doi:  dx.doi.org/10.1021/acs.joc.5b01217]

Conjugate Addition of Diboron Catalyzed by O -Monoacyltartaric Acids
Sugiura, M.; Ishikawa, W.; Kuboyama, Y.; Nakajima, M.
Synthesis 2015, 47, 2265-2269
[doi: dx.doi.org/10.1055/s-0034-1378835]

p-Cresyl sulfate, a uremic toxin, causes vascular endothelial and smooth muscle cell damages by inducing oxidative stress
Watanabe, H.; Miyamoto, Y.; Enoki, Y.; Ishima, Y.; Kadowaki, D.; Kotani, S.; Nakajima, M.; Tanaka, M.; Matsushita, K.; Mori, Y.; Kakuta, T.; Fukagawa, M.; Otagiri, M.; Maruyama, T.
Pharmacology Research and Perspectives, 2015, 3. 1-12
[doi: doi.org/10.1002/prp2.92]

Chiral Lithium Binaphtholate for Enantioselective Michael Addition of Acyclic α-Alkyl-β- Keto Esters to Vinyl Ketones
Kotani, S.; Moritani, M.; Nakajima, M.
Asian J. Org. Chem. 2015, 4, 616-618
[doi: doi.org/10.1002/ajoc.201500122]

Human organic anion transporters function as a high-capacity transporter for p-cresyl sulfate, a uremic toxin
Watanabe, H., Sakaguchi, Y., Sugimoto, R., Kaneko, K.; Iwata, H.; Kotani, S.; Nakajima, M.; Ishima, Y.; Otagiri, M.; Maruyama, T.
Clin. Exp. Nephrol. 2014, 18, 814-820
[doi: dx.doi.org/10.1007/s10157-013-0902-9]

O-monoacyltartaric acid catalyzed enantioselective conjugate addition of a boronic acid to dienones: Application to the synthesis of optically active cyclopentenones
Sugiura, M.; Kinoshita, R.; Nakajima, M.
Org. Lett. 2014, 16, 5172-5175
[doi: 10.1021/ol502526y]

Phosphine oxide-catalyzed enantioselective intramolecular aldol reaction via regioselective enolization of unsymmetrical diketones with tetrachlorosilane
Kotani, S.; Aoki, S.; Sugiura, M.; Ogasawara, M.; Nakajima, M.
Org. Lett. 2014, 16, 4802-4805
[doi: 10.1021/ol502269w]

Imino ene-type reaction of enamines with N-sulfonylimines and application to diastereoselective synthesis of N-sulfonyl-1,3-diamines
Ito, M.; Kashiwagi, T.; Kotani, S.; Nakajima, M.; Sugiura, M.
Tetrahedron Lett. 2014, 55, 4082-4085
[doi: doi.org/10.1016/j.tetlet.2014.05.123]

Lithium binaphtholate-catalyzed asymmetric addition of lithium acetylides to carbonyl compounds
Kotani, S.; Kukita, K.; Tanaka, K.; Ichibakase, T.; Nakajima, M.
J. Org. Chem. 2014, 79, 4817-4825

[doi: 10.1021/jo5005394]

Diastereoselective synthesis of 1,3-diamines by a domino reaction of imines, enamines, and trichlorosilane
Kashiwagi, T., Kotani, S., Nakajima, M., Sugiura, M.
Tetrahedron Lett. 2014, 55, 1924-1926
[doi: doi.org/10.1016/j.tetlet.2014.01.152]

Enantioselective double aldol reactions involving the sequential activation of silicon tetrachloride by chiral phosphine oxides
Kotani, S.; Sugiura, M.; Nakajima, M.
Synlett 2014, 25. 631-640
[doi: 10.1055/s-0033-1340600]

Atropisomeric chiral dienes in asymmetric catalysis: C2 – symmetric (Z,Z)-2,3-Bis[1- (diphenylphosphinyl)ethylidene]tetralin as a highly active lewis base organocatalyst
Ogasawara, M.; Kotani, S.; Nakajima, H.; Furusho, H.; Miyasaka, M.; Shimoda, Y.; Wu. W.Y.; Sugiura, M.; Takahashi, T.; Nakajima, M.
Angew. Chem. In. Ed. 2013. 52, 13798- 13802
[doi: doi.org/10.1002/anie.201308112]

Enantioselective Morita-Baylis-Hillman reaction catalyzed by a chiral phosphine oxide
Kotani, S.; Ito, M.; Nozaki, H. Sugiura, M.; Ogasawara, M.; Nakajima, M.
Tetrahedron Lett. 2013, 54, 6430-6433
[doi; doi.org/10.1016/j.tetlet.2013.09.067]

Facile synthesis of chiral 1,2-chlorohydrins via the ring-opening of meso-epoxides catalyzed by chiral phosphine oxides
Kotani, S.; Furusho, H.; Sugiura, M.; Nakajima, M.
Tetrahedron 2013, 69, 3075-3081
[doi: doi.org/10.1016/j.tet.2013.01.066]

Stereoselective synthesis of multiple stereocenters by using a double aldol reaction
Shimoda, Y.; Kubo, T.; Sugiura, M.; Kotani, S.; Nakajima, M.
Angew. Chem. In. Ed. 2013, 52, 3461-3464
[doi: doi.org/10.1002/anie.201209848]

Enantioselective aldol reactions catalyzed by chiral phosphine oxides
Kotani, S.; Sugiura, M.; Nakajima, M.
Chem. Rec. 2013, 13, 362-370
[doi: doi.org/10.1002/tcr.201300004]

P-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase
Watanabe, H.; Miyamoto, Y.; Honda, D.; Tanaka, H.; Wu, Q.; Endo, M.; Noguchi, T.; Kadowaki, D.; Ishima, Y.; Kotani, S.; Nakajima, M.; Kataoka, K.; Kim-Matsuyama, S.; Tanaka, M.; Fukagawa, M.; Otagiri, M. Maruyama, T.
Kidney International 2013, 83, 582-592
[doi:doi.org/10.1038/ki.2012.448]

4.10 Enantioselective Aldol Reactions Catalyzed by Chiral Lewis Bases
Nakajima, M.
Comprehensive Chirality 4, pp. 198-209

6.8 Allylations of C-O and C-N Double Bonds and Related Reactions
Sugiura, M., Nakajima, M.
Comprehensive Chirality 6, pp. 214-233

6.21 C-X Bond Formation: Organocatalytic Enantioselective Halogenation of meso Epoxides
Kotani, S., Nakajima, M.
Comprehensive Chirality 6, pp. 506-517

Enantioselective reductive aldol reaction using tertiary amine as hydride donor
Osakama, K.; Sugiura, M.; Nakajima, M.; Kotani, S.
Tetrahedron Lett. 2012, 53, 4199-4201
[doi: doi.org/10.1016/j.tetlet.2012.05.147]

Efficient preparation of 1,3-Diol derivatives with three contiguous stereocenters by an enantioselective direct aldol-tishchenko reaction
Ichibakase, T.; Nakajima, M.
Synthesis 2012, 44, 3145-3151
[doi: 10.1055/s-0031-1291138]

Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin
Watanabe, H.; Noguchi, T.; Miyamoto, Y.; Kadowaki, D.; Kotani, S.; Malako,a. M.; Miyamura, S.; Ishima, Y.; Otagiri, M.; Maruyama, T.
Drug Metab. Dispos. 2012, 40, 1423-1428
[doi: doi.org/10.1124/dmd.112.045617]

Synthesis of aryl group-modified DIOP dioxides (Ar-DIOPOs) and their application as modular Lewis base catalysts
Ohmaru, Y.; Sato, N.; Mizutani, M.; Kotani, S.; Sugiura, M.; Nakajima, M.
Org. Biomol. Chem. 2012, 10, 4562-4570
[doi: 10.1039/C2OB25338K]

Trichlorosilyl triflate-mediated enantioselective directed cross-aldol reaction between ketones using a chiral phosphine oxide as an organocatalyst
Aoki, S.; Kotani, S.; Sugiura, M.; Nakajima, M.
Chem. Commun. 2012, 48, 5524-5526
[doi: 10.1039/C2CC31543B]

Construction of quaternary carbon centers by a base-catalyzed enantioselective aldol reaction and related reactions of trimethoxysilyl enol ethers
Ichibakase, T.; Kaneko, T.; Orito, Y.; Kotani, S.; Nakajima, M
Tetrahedron 2012, 68, 4210-4224
[doi: doi.org/10.1016/j.tet.2012.03.096]

A tertiary amine as a hydride donor: Trichlorosilyl triflate-mediated conjugate reduction of unsaturated ketones
Kotani, S.; Osakama, K.; Sugiura, M.; Nakajima, M.
Org. Lett. 2011, 13, 3968-3971
{doi: 10.1021/ol2014895]

Organic anion transporters play an important role in the uptake of p-cresyl sulfate, a uremic toxin, in the kidney
Miyamoto, Y.; Watanabe, H.; Noguchi, T.;Kotani, S.; Nakajima, M.; Kadowaki, D.;Otagiri, M.; Maruyama, T.
Nephrol. Dial. Transplant. 2011, 26, 2498-2502
[doi: doi.org/10.1093/ndt/gfq785]

Enantioselective double aldol reaction catalyzed by chiral phosphine oxide
Shimoda, Y.; Kotani, S.; Sugiura, M.; Nakajima, M.
Chem. Eur. J. 2011, 17, 7992-7995
[doi: doi.org/10.1002/chem.201100917]

Enantioselective evans-tishchenko reduction of β-hydroxyketone catalyzed by lithium binaphtholate
Ichibakase, T.; Nakatsu, M.; Nakajima, M.
Molecules 2011, 16, 5008-5019
[doi: doi.org/10.3390/molecules16065008]

Trichlorosilyl triflate for enantioselective direct-type aldol reaction with chiral phosphine oxide
Kotani, S.; Aoki, S.; Sugiura, M.; Nakajima, M.
Chem. Commun. 2011, 47, 5614-5616
[doi: doi.org/10.1016/j.tetlet.2011.03.095]

Direct enantioselective aldol-tishchenko reaction catalyzed by chiral lithium diphenylbinaphtholate
Ichibakase, T.; Nakajima, M.
Org. Lett. 2011, 13, 1579-1581
[doi: 10.1021/ol103156h]

Synthesis of γ-amino alcohols from aldehydes, enamines, and trichlorosilane using Lewis base catalysts
Kashiwagi, T.; Kotani, S.; Sugiura, M.; Nakajima, M.
Tetrahedron 2011, 67, 531-539
[doi:doi.org/10.1016/j.tet.2010.10.075]

Enantioselective conjugate addition of boronic acids to enones catalyzed by O- monoacyltartaric acids
Sugiura, M.; Tokudomi, M.; Nakajima, M.
Chem. Commun. 2010, 46, 7799-7800
[doi: 10.1039/C0CC03076G]

Sterically congested, “roofed” β-iminodisulfides as new chiral ligands for palladium- catalyzed, asymmetric allylic alkylation
Matsunaga, H.; Tokuda, R.; Nakajima, M.; Ishizuka, T.
Chem. Pharm. Bull. 2010, 58, 1419-1421
[doi: doi.org/10.1248/cpb.58.1419]

Enantioselective alkynylation of carbonyl compounds with trimethoxysilylalkynes catalyzed by lithium binaphtholate
Ueda, T.; Tanaka, K.; Ichibakase, T.; Orito, Y.; Nakajima, M.
Tetrahedron 2010, 66, 7726-7731
[doi: doi.org/10.1016/j.tet.2010.07.080]

Development of chiral dinitrones as modular Lewis base catalysts: Asymmetric allylation of aldehydes with allyltrichlorosilanes
Oh, Y. S.; Kotani, S.; Sugiura, M.; Nakajima, M.
Tetrahedron: Asymmetry 2010, 21, 1833-1835
[doi: doi.org/10.1016/j.tetasy.2010.05.048]

DMAP-catalyzed cyanation of aldehydes and ketones with ethyl cyanoformate
Aoki, S.; Kotani, S.; Sugiura, M.; Nakajima, M.
Tetrahedron Lett. 2010, 51, 3547-3549
[doi: doi.org/10.1016/j.tetlet.2010.04.123]

Enantioselective alkynylation of ketones with trimethoxysilylalkynes using lithium binaphtholate as a catalyst
Tanaka, K.; Ueda, T.; Ichibakase, T.; Nakajima, M.
Tetrahedron Lett. 2010, 51, 2168-2169
[doi: doi.org/10.1016/j.tetlet.2010.02.084]

Diastereo- and enantioselective reductive aldol reaction with trichlorosilane using Chiral Lewis bases as organocatalysts
Sugiura, M.; Sato, N.; Sonoda, Y.; Kotani, S.; Nakajima, M.
Chem. Asian J. 2010, 5, 478-481
[doi: doi.org/10.1002/asia.200900450]

2004〜2009年

Novel enantioselective direct aldol-type reaction promoted by a chiral phosphine oxide as an organocatalyst
Kotani, S.; Shimoda, Y.; Sugiura, M.; Nakajima, M.
Tetrahedron Lett. 2009, 50, 4602-4605
[doi: doi.org/10.1016/j.tetlet.2009.05.065]

Asymmetric synthesis of 4H-1,3-oxazines: Enantioselective reductive cyclization of N- acylated β-amino enones with trichlorosilane catalyzed by chiral Lewis bases
Sugiura, M.; Kumahara, M.; Nakajima, M.
Chem. Commun. 2009, 3585-3587
[doi: 10.1039/B905102C]

Enantioselective aldol reaction of silyl ketene acetals promoted by a Lewis base-activated Lewis acid catalyst
Shimoda, Y.; Tando, T.; Kotani, S.; Sugiura, M.; Nakajima, M.
Tetrahedron: Asymmetry 2009, 20, 1369-1370
[doi: doi.org/10.1016/j.tetasy.2009.05.028]

A chiral “roofed” cis-diamine-Ru(II) complex: An efficient catalyst for asymmetric transfer hydrogenation of ketimines
Matsunaga, H.; Nakanishi, K.; Nakajima, M.; Kunieda, T.; Ishizuka, T.
Heterocycles 2008, 78, 617-622
[doi: doi.org/10.1002/chin.200929063]

Lewis base-catalyzed conjugate reduction and reductive aldol reaction of α,β-unsaturated ketones using trichlorosilane
Sugiura, M.; Sato, N.; Kotani, S.; Nakajima, M.
Chem. Commun. 2008, 4309-4311
[doi: 10.1039/B807529H]

Enantioselective construction of quaternary asymmetric carbon centers using an aldol reaction of trimethoxysilyl enol ethers catalyzed by lithium binaphtholate
Ichibakase, T.; Orito, Y.; Nakajima, M.
Tetrahedron Lett. 2008, 49, 4427-4429
[doi: doi.org/10.1016/j.tetlet.2008.05.004]

First asymmetric Abramov-type phosphonylation of aldehydes with trialkyl phosphites catalyzed by chiral Lewis bases
Nakanishi, K.; Kotani, S.; Sugiura, M.; Nakajima, M.
Tetrahedron 2008, 64, 6415-6419
[doi: doi.org/10.1016/j.tet.2008.04.078]

Chiral phosphine oxide BINAPO as a Lewis base catalyst for asymmetric allylation and aldol reaction of trichlorosilyl compounds
Kotani, S.; Hashimoto, S.; Nakajima, M.
Tetrahedron 2007, 63, 3122-3132
[doi: doi.org/10.1016/j.tet.2007.02.014]

Catalytic enantioselective tandem carbonyl ylide formation/1,3 dipolar cycloaddition reactions of α-diazo ketones with aromatic aldehydes using dirhodium(II) tetrakis[N- benzene-fusedphthaloyl- (S)-valinate]
Tsutsui, H.; Shimada, N.; Abe, T.;Anada, M.; Nakajima, M.; Nakamura, S.; Nambu, H.; Hashimoto, S.
Adv. Synth. Catal. 2007, 349, 521-526
[doi: doi.org/10.1002/adsc.200600591]

Lewis base catalyzed asymmetric reactions involving hypervalent silicate intermediates
Orito, Y.; Nakajima, M.
Synthesis 2006, 11, 1391-1401
[doi: 10.1055/s-2006-926405]

Enantioselective aldol reactions of trichlorosilyl enol ethers catalyzed by the chiral phosphine oxide BINAPO
Kotani, S.; Hashimoto, S.; Nakajima, M.
Synlett 2006, 4, 1116-1118
[doi: 10.1055/s-2006-939725]

Chiral base-catalyzed aldol reaction of trimethoxysilyl enol ethers: Effect of water as an additive on stereoselectivities
Orito, Y.; Hashimoto, S.; Ishizuka, T.; Nakajima, M.
Tetrahedron 2006, 62, 390-400
[doi: doi.org/10.1016/j.tet.2005.09.074]

Sterically congested “roofed” 2-iminothioethers as new chiral ligands for palladium- catalyzed asymmetric allylic alkylation
Tokuda, R.; Matsunaga, H.; Ishizuka, T.; Nakajima, M.; Kunieda, T.
Heterocycles 2005, 66, 135-141
[doi: 10.3987/COM-05-S(K)50]

Asymmetric ring opening of meso-epoxides catalyzed by the chiral phosphine oxide BINAPO
Tokuoka, E.; Kotani, S.; Matsunaga, H.; Ishizuka, T.; Hashimoto, S.; Nakajima, M.
Tetrahedron: Asymmetry 2005, 16, 2391-2392
[doi: doi.org/10.1016/j.tetasy.2005.06.021]

Sterically congested ‘roofed’ 2-thiazolines as new chiral ligands for copper(II)-catalyzed asymmetric Diels-Alder reactions
Yamakuchi, M.; Matsunaga, H.; Tokuda, R.;Ishizuka, T.; Nakajima, M.; Kunieda, T.
Tetrahedron Lett. 2005, 46, 4019-4022
[doi: doi.org/10.1016/j.tetlet.2005.04.025]

Chiral phosphine oxide BINAPO as a catalyst for enantioselective allylation of aldehydes with allyltrichlorosilanes
Nakajima, M.; Kotani, S.; Ishizuka, T.; Hashimoto, S.
Tetrahedron Lett. 2005, 46, 157-159
[doi: doi.org/10.1016/j.tetlet.2004.10.168]

Enantioselective aldol reaction of trimethoxysilyl enol ether catalyzed by lithium binaphtholate
Nakajima, M.; Orito, Y.; Ishizuka, T.; Hashimoto, S.
Org. Lett. 2004, 6, 3763-3765
[doi: 10.1021/ol048485+]

A new dirhodium(II) carboxamidate complex as a chiral Lewis acid catalyst for enantioselective hetero-Diels-Alder reactions
Anada, M.; Washio, T.; Shimada, N.; Kitagaki, S.; Nakajima, M.;Shiro, M.; Hashimoto, S.
Angew. Chem. In. Ed. 2004, 43, 2665-2668
[doi: doi.org/10.1002/anie.200453821]

Enantioselective aldol reactions of trichlorosilyl enol ethers catalyzed by chiral N,N′-dioxides and monodentate N-oxides
Nakajima, M.; Yokota, T.; Saito, M.; Hashimoto, S.
Tetrahedron Lett. 2004, 45, 61-64
[doi: doi.org/10.1016/j.tetlet.2003.10.114]